Proximal femoral fractures are common in elderly osteoporosis patients; however, its prevalence is clinically rare in hip fracture patients with hip osteoarthritis (OA). This study aimed to evaluate bone strength of the proximal femur with or without hip OA and proximal femoral fracture risk using computed tomography (CT)-based finite element analysis (FEA). A retrospective analysis was done on CT data of 20 patients who underwent total hip arthroplasty for unilateral hip OA. Furthermore, the fracture load between OA and contralateral sides was compared and the association between fracture load and risk factor was analyzed. The fracture load was significantly higher in the OA side than that in the contralateral side (3819.5 ± 1557.8 N vs. 3224.5 ± 943.7 N, respectively; P = 0.0405). There was no significant difference in fracture load between OA and the contralateral side in Kellgren-Lawrence (KL)-3 and KL-4 grade, but the KL-4 fracture load tends to be high (P = 0.2461 and P = 0.0527, respectively). Moreover, there was no significant association between fracture load and OA severity or age. The study findings may assist in predicting bone strength and proximal femur fracture risk. The results of this FEA study indicate the bone strength of the proximal femur was affected by the severity of the osteoarthritis.

中文翻译：

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通过基于计算机断层扫描的有限元分析，对有或没有髋骨关节炎的股骨近端骨强度进行比较研究。

股骨近端骨折常见于老年骨质疏松症患者。然而，在患有髋骨关节炎（OA）的髋部骨折患者中，其患病率在临床上很少见。这项研究的目的是使用基于计算机断层扫描（CT）的有限元分析（FEA）评估有或没有髋骨OA的股骨近端的骨强度和股骨近端骨折的风险。回顾性分析了20例接受单侧髋骨关节炎全髋关节置换术的患者的CT数据。此外，比较了OA和对侧的骨折负荷，并分析了骨折负荷与危险因素之间的关系。OA侧的骨折负荷显着高于对侧（分别为3819.5±1557.8 N和3224.5±943.7 N； P = 0.0405）。Kellgren-Lawrence（KL）-3和KL-4级的OA和对侧的骨折负荷没有显着差异，但KL-4的骨折负荷往往较高（分别为P = 0.2461和P = 0.0527） ）。而且，骨折负荷与骨关节炎严重程度或年龄之间没有显着关联。研究结果可能有助于预测骨强度和股骨近端骨折的风险。这项FEA研究的结果表明，股骨近端的骨强度受到骨关节炎严重程度的影响。研究结果可能有助于预测骨强度和股骨近端骨折的风险。这项FEA研究的结果表明，股骨近端的骨强度受到骨关节炎严重程度的影响。研究结果可能有助于预测骨强度和股骨近端骨折的风险。这项FEA研究的结果表明，股骨近端的骨强度受骨关节炎严重程度的影响。