BACKGROUND COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including chloroquine. We report here the clinical features and therapeutic course of the first reported patient with confirmed COVID-19 pneumonia that recovered in Colombia, after the use of chloroquine and clarithromycin. CASE PRESENTATION A 34-year-old male, returning from Spain, presented with complaints of fever, and cough, and class-II obesity, being hospitalized. The respiratory viruses and bacteria tested by FilmArray® PCR were negative. Two days later, clarithromycin was started because the patient was suspected as community-acquired pneumonia. At the third day, the rRT-PCR confirmed the SARS-CoV-2 infection. A day later, chloroquine was started because of that. His chest computed tomography was performed and showed bilateral multifocal ground-glass opacities with consolidation, which suggested viral pneumonia as a differential diagnosis. Progressively his clinical condition improved and at day 9, patient rRT-PCR for SARS-CoV-2 became negative. The patient was discharged and isolated at home per 14 days. CONCLUSIONS Our patient improved significantly. This and other COVID-19 cases are urgently demanding results from clinical trials that support evidence-based therapeutical approaches to this pandemic and the clinical management of patients, especially those at critical care.

中文翻译：

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接受氯喹和克拉霉素治疗的哥伦比亚一名患者成功恢复了COVID-19肺炎。

背景技术COVID-19大流行是对公共卫生和传染病临床医生的挑战，特别是对于尚未充分定义的治疗方法。在这种情况下，正在使用包括氯喹在内的研究药物。我们在这里报告使用氯喹和克拉霉素后在哥伦比亚康复的首例确诊的COVID-19肺炎的首次报告患者的临床特征和治疗过程。病例介绍一名34岁的男性，从西班牙返回，表现出发烧，咳嗽和II类肥胖的症状，正在住院治疗。通过FilmArray®PCR检测的呼吸道病毒和细菌为阴性。两天后，开始克拉霉素治疗，因为该患者被怀疑是社区获得性肺炎。第三天 rRT-PCR证实了SARS-CoV-2感染。一天之后，因此开始使用氯喹。他进行了胸部计算机断层扫描，发现双侧多灶性磨玻璃样混浊伴有巩固，提示病毒性肺炎可作为鉴别诊断。他的临床病情逐渐好转，第9天，SARS-CoV-2的患者rRT-PCR变为阴性。该患者每14天出院并隔离一次。结论我们的患者明显改善。该和其他COVID-19病例迫切需要临床试验的结果，这些试验支持针对这种流行病和患者（尤其是重症监护患者）的临床管理的循证治疗方法。他进行了胸部计算机断层扫描，发现双侧多灶性磨玻璃样混浊伴有巩固，提示病毒性肺炎可作为鉴别诊断。他的临床病情逐渐好转，第9天，SARS-CoV-2的患者rRT-PCR变为阴性。该患者每14天出院并隔离一次。结论我们的患者明显改善。该和其他COVID-19病例迫切需要临床试验的结果，这些试验支持针对这种流行病和患者（尤其是重症监护患者）的临床管理的循证治疗方法。他进行了胸部计算机断层扫描，发现双侧多灶性磨玻璃样混浊伴有巩固，提示病毒性肺炎可作为鉴别诊断。他的临床病情逐渐好转，第9天，SARS-CoV-2的患者rRT-PCR变为阴性。该患者每14天出院并隔离一次。结论我们的患者明显改善。该和其他COVID-19病例迫切需要临床试验的结果，这些试验支持针对这种流行病和患者（尤其是重症监护患者）的临床管理的循证治疗方法。该患者每14天出院并隔离一次。结论我们的患者明显改善。该和其他COVID-19病例迫切需要临床试验的结果，这些试验支持针对这种流行病和患者（尤其是重症监护患者）的临床管理的循证治疗方法。该患者每14天出院并隔离一次。结论我们的患者明显改善。该和其他COVID-19病例迫切需要临床试验的结果，这些临床试验支持针对这种流行病和患者（尤其是重症监护患者）的临床管理的循证治疗方法。