Chronic endometritis (CE) is an unusual inflammatory condition characterized by endometrial plasmacyte infiltration. It has a high prevalence in women with reproductive failure. Because of its characteristic localization patterns and molecular functions, syndecan‐1 has been identified as a biomarker of plasmacyte, and syndecan‐1 immunohistochemistry (IHC) becomes the most dependable diagnostic method for CE. In this review, we discuss the association between CE and reproductive failure, the clinicopathological characterization of CE, the function and expression of syndecan‐1, the progress of syndecan‐1 IHC in the diagnosis of CE, and the prediction of reproductive outcome.

中文翻译：

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慢性子宫内膜炎和生殖衰竭：syndecan-1 的作用。

慢性子宫内膜炎 (CE) 是一种不寻常的炎症性疾病，其特征是子宫内膜浆细胞浸润。它在生殖失败的女性中患病率很高。由于其特有的定位模式和分子功能，syndecan-1 已被确定为浆细胞的生物标志物，syndecan-1 免疫组织化学 (IHC) 成为最可靠的 CE 诊断方法。在这篇综述中，我们讨论了 CE 与生殖失败的关系、CE 的临床病理特征、syndecan-1 的功能和表达、syndecan-1 IHC 在 CE 诊断中的进展以及对生殖结果的预测。