OBJECTIVE To present recent evidence on the prevalence, incidence, costs, activity limitations, and work limitations of common conditions requiring rehabilitation. METHODS This was a systematic review. Medline (PubMed), SCOPUS, Web of Science, and the grey literature were searched for relevant articles about amputation, osteoarthritis, rheumatoid arthritis, back pain, multiple sclerosis, spinal cord injury, stroke, and traumatic brain injury. Two investigators independently reviewed articles and selected those for inclusion. Quality grading was performed using the Methodological Evaluation of Observational Research Checklist and Newcastle-Ottawa Quality Assessment Form. RESULTS 110 articles were included. The prevalence of back pain in the past 3 months is 33.9% among community-dwelling adults, and patients with back pain contribute $365 billion in all-cause medical costs. Osteoarthritis is the next most prevalent condition (approximately 10.4%), and patients with this condition contribute $460 billion in all-cause medical costs. These two conditions are the most prevalent and costliest (medically) of the illnesses explored here. Stroke follows these conditions in both prevalence (2.5-3.7%) and medical costs ($28 billion). Other conditions may have a lower prevalence but are associated with relatively higher per capita effects. CONCLUSION Consistent with previous findings, back pain and osteoarthritis are the most prevalent conditions with large aggregate medical costs. By contrast, other conditions have a lower prevalence or cost but relatively higher per capita costs and effects on activity and work. The data are extremely heterogeneous which makes anything beyond broad comparisons challenging: additional information is needed to determine the relative impact of each condition.

中文翻译：

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对美国截肢、骨关节炎、类风湿关节炎、背痛、多发性硬化症、脊髓损伤、中风和创伤性脑损伤的发病率、患病率、费用和活动/工作限制的系统回顾：2019 年更新

目的 提供有关需要康复的常见病症的患病率、发生率、费用、活动限制和工作限制的最新证据。方法 这是一项系统评价。在 Medline (PubMed)、SCOPUS、Web of Science 和灰色文献中检索有关截肢、骨关节炎、类风湿性关节炎、背痛、多发性硬化症、脊髓损伤、中风和创伤性脑损伤的相关文章。两名研究人员独立审查文章并选择纳入。使用观察研究清单的方法学评估和纽卡斯尔-渥太华质量评估表进行质量分级。结果 纳入 110 篇文章。过去 3 个月，社区居住的成年人背痛患病率为 33.9%，背痛患者的全因医疗费用高达 3650 亿美元。骨关节炎是第二常见的疾病（约 10.4%），患有这种疾病的患者承担了 4600 亿美元的全因医疗费用。这两种情况是这里探讨的疾病中最普遍和最昂贵（医学上）的。中风的患病率 (2.5-3.7%) 和医疗费用 (280 亿美元) 均紧随这些疾病。其他疾病的患病率可能较低，但人均影响相对较高。结论 与之前的研究结果一致，背痛和骨关节炎是最普遍的疾病，总医疗费用很高。相比之下，其他疾病的患病率或成本较低，但人均成本和对活动和工作的影响相对较高。数据极其异构，这使得超出广泛比较的任何事情都具有挑战性：需要额外的信息来确定每种条件的相对影响。