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Metabolic Syndrome and psoriatic arthritis: considerations for the clinician.
Expert Review of Clinical Immunology ( IF 3.9 ) Pub Date : 2020-04-01 , DOI: 10.1080/1744666x.2020.1740593
Francesco Caso 1 , Maria Sole Chimenti 2 , Luca Navarini 3 , Piero Ruscitti 4 , Rosario Peluso 1 , Nicolò Girolimetto 1, 5 , Antonio Del Puente 1 , Roberto Giacomelli 4 , Raffaele Scarpa 1 , Luisa Costa 1
Affiliation  

Introduction: Metabolic Syndrome (MetS) is strictly interconnected with systemic inflammation, and increased evidence has described a close link between this condition and Psoriatic Arthritis (PsA).Areas covered: This review summarizes main studies exploring clinical aspects and prevalence of MetS in PsA cohorts. Further, there is accumulating evidence showing shared inflammatory pathways between MetS, its components, and PsA.Expert opinion: The high prevalence of MetS in PsA highlights the need for screening, evaluation, and close monitoring of MetS and its components (namely, diabetes mellitus, obesity, hypertension, and dyslipidemia) in psoriatic patients.Further studies should focus on the pathogenetic link between MetS and PsA. More studies are required to identify appropriate algorithms for the assessment and management of MetS in PsA patients.

中文翻译:

代谢综合征和银屑病关节炎:临床医生的考虑。

简介:代谢综合征 (MetS) 与全身炎症密切相关,越来越多的证据描述了这种情况与银屑病关节炎 (PsA) 之间的密切联系。 涵盖领域:本综述总结了探索 PsA 队列中 MetS 的临床方面和患病率的主要研究. 此外,越来越多的证据表明 MetS 及其组成部分和 PsA 之间存在共同的炎症通路。 、肥胖、高血压和血脂异常)在银屑病患者中。进一步的研究应该集中在 MetS 和 PsA 之间的发病机制上。
更新日期:2020-04-23
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