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The immunopathobiology of T cells in stress condition: a review.
Cell Stress and Chaperones ( IF 3.3 ) Pub Date : 2020-04-21 , DOI: 10.1007/s12192-020-01105-0
Mostafa Khedri 1, 2 , Azam Samei 1 , Mahdi Fasihi-Ramandi 3 , Ramezan Ali Taheri 2
Affiliation  

Several factors impact the immune responses such as the chemical nature of antigens, the physiologic and metabolic condition of the responsive cells, the site of antigen recognition, and neuroendocrine and pharmacological received agents. Incompatibility of host immune responses to the entrapped antigens leads to an immune pathological manner instead of an immune protection which results in the disharmony of the immune effective factors. Besides the fact that stress is one of the most common effective factors in human life, it also contributed to the protection, suppression, and pathology of the immune system. In this review article, the direct and indirect effects of the stress on the function of T cells and the contributed mechanism of action will be discussed.

中文翻译:


应激条件下 T 细胞的免疫病理学:综述。



有几个因素影响免疫反应,例如抗原的化学性质、反应细胞的生理和代谢状况、抗原识别位点以及神经内分泌和药理学接受的试剂。宿主对所捕获的抗原的免疫反应不相容,导致免疫病理方式而不是免疫保护,从而导致免疫有效因子的不协调。压力除了是人类生活中最常见的有效因素之一之外,还有助于免疫系统的保护、抑制和病理。在这篇综述文章中,将讨论应激对 T 细胞功能的直接和间接影响及其作用机制。
更新日期:2020-04-21
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