Plasmodium vivax is an important cause of malaria, associated with a significant public health burden. Whilst enhanced malaria-control activities have successfully reduced the incidence of Plasmodium falciparum malaria in many areas, there has been a consistent increase in the proportion of malaria due to P. vivax in regions where both parasites coexist. This article reviews the epidemiology and biology of P. vivax, how the parasite differs from P. falciparum, and the key features that render it more difficult to control and eliminate. Since transmission of the parasite is driven largely by relapses from dormant liver stages, its timely elimination will require widespread access to safe and effective radical cure.

中文翻译：

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恶性疟原虫地图缩小时代的间日疟原虫。

间日疟原虫是疟疾的重要病因，与重大的公共卫生负担有关。虽然加强疟疾控制活动已在许多地区成功降低了恶性疟原虫疟疾的发病率，但在两种寄生虫共存的地区，间日疟原虫引起的疟疾比例持续增加。本文回顾了间日疟原虫的流行病学和生物学、寄生虫与恶性疟原虫的区别，以及使其更难控制和消除的主要特征。由于寄生虫的传播主要是由休眠肝脏阶段的复发驱动的，因此及时消除寄生虫需要广泛获得安全有效的根治方法。