Various environmental factors affect livestock production but heat stress is a major challenge in the poultry farming. Poultry exposes to high temperature alters blood immunological parameters and liver enzymatic function which in turn, suppress the immunity and disease resistance of chickens. Thus, the purpose of present study was to explore the effect of dietary curcumin supplementation on blood immunological biomarker and liver enzymatic activity of laying hens under heat stress conditions. Experimental groups contained two control groups (normal temperature control (NC) and heat stress control (HC) and 3 heat stress curcumin treatment groups (HT100, HT200 and HT300). Hens in HC group with basal diet and heat stress curcumin treatment groups were exposed 6 h/day heat stress (32 ± 1 °C) from 10:00 a.m. to 16:00 p.m. for 9 week. The results of present study showed that heat stressed curcumin treatment group had improved liver weight, WBC values and immunoglobulin level as compared to untreated HC and NC groups. The available results also indicated that laying hens supplemented with curcumin under high temperature conditions had reduced H/L ratio, serum corticosterone levels, inflammatory cytokines response and liver enzymatic activity (ALT) which enhanced the immunity of laying hens under hot climatic conditions. Therefore, it is concluded that curcumin has ability to combat harsh environmental conditions which can be used as anti-inflammatory and immune booster feed additive in the poultry nutrition.

中文翻译：

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日粮姜黄素对高温条件下蛋鸡血液免疫学特征和肝脏酶活性的影响

各种环境因素影响牲畜生产，但热应激是家禽养殖的主要挑战。家禽暴露在高温下会改变血液免疫学参数和肝脏酶功能，进而抑制鸡的免疫力和抗病能力。因此，本研究的目的是探讨日粮补充姜黄素对热应激条件下蛋鸡血液免疫生物标志物和肝脏酶活性的影响。实验组包括2个对照组（常温控制（NC）和热应激控制（HC）和3个热应激姜黄素处理组（HT100、HT200和HT300）。HC组母鸡基础日粮和热应激姜黄素处理组）从上午 10:00 到下午 16:00 进行 6 小时/天的热应激 (32 ± 1 °C)，持续 9 周。本研究的结果表明，与未治疗的 HC 和 NC 组相比，热应激姜黄素治疗组的肝脏重量、WBC 值和免疫球蛋白水平有所改善。现有结果还表明，在高温条件下补充姜黄素的蛋鸡降低了 H/L 比、血清皮质酮水平、炎症细胞因子反应和肝酶活性 (ALT)，从而增强了蛋鸡在炎热气候条件下的免疫力​​。因此，得出结论，姜黄素具有抵抗恶劣环境条件的能力，可用作家禽营养中的抗炎和免疫增强饲料添加剂。现有结果还表明，在高温条件下补充姜黄素的蛋鸡降低了 H/L 比、血清皮质酮水平、炎症细胞因子反应和肝酶活性 (ALT)，从而增强了蛋鸡在炎热气候条件下的免疫力​​。因此，得出结论，姜黄素具有抵抗恶劣环境条件的能力，可用作家禽营养中的抗炎和免疫增强饲料添加剂。现有结果还表明，在高温条件下补充姜黄素的蛋鸡降低了 H/L 比、血清皮质酮水平、炎症细胞因子反应和肝酶活性 (ALT)，从而增强了蛋鸡在炎热气候条件下的免疫力​​。因此，得出结论，姜黄素具有抵抗恶劣环境条件的能力，可用作家禽营养中的抗炎和免疫增强饲料添加剂。