PHEMs with intact structured melanosomes were observed in TEM before PTPD‐12 treatment. After treatment with PTPD‐12 (20 μM) for 24 hours, melanosomes were subject to degradation and the number of autophagic vacuoles (magnified image) increased. Magnified images on the right panel are from the area indicated by the red box (I, II)

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封面图片

在PTPD-12处理之前，在TEM中观察到具有完整结构的黑色素体的PHEM。用PTPD-12（20μM）处理24小时后，黑素体遭到降解，自噬泡的数量（放大的图像）增加。右侧面板上的放大图像来自红色框（I，II）指示的区域