Recent advances in medical radiation technologies have enabled small field radiotherapy with a beam size as small as a few millimeters for precise dose delivery to patients. However, conventional radiation dosimeters for small field radiotherapy suffer from inaccurate dose measurements due to their large absorber size. Herein, we present a nanofabricated chip calorimeter as a new platform for a miniaturized dosimeter for measurements of the absorbed dose. The calorimeter consists of a microscale absorber body built with a SU-8 photoresist and a microfluidic water container. The measurement system was constructed such that the calorimeter operates in the heat compensation mode, where the temperature change of the absorber was proportional to the absorbed energy. The operability of the heat compensation calorimeter was examined with electric heating and a visible light source. The feasibility of application of the microfluidic chip calorimeter for medical radiation sensor was successfully demonstrated by measuring the absorbed dose from the small radiation field of the Gamma Knife.

中文翻译：

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用于小场辐射剂量测定的微流控芯片量热仪

医疗辐射技术的最新进展使小范围放射治疗成为可能，其射束尺寸小至几毫米，可为患者提供精确的剂量输送。然而，用于小场放射治疗的常规辐射剂量计由于其大吸收体尺寸而遭受不准确的剂量测量。在此，我们提出了一种纳米制造的芯片热量计，作为用于测量吸收剂量的小型化剂量计的新平台。热量计由一个用 SU-8 光刻胶制成的微型吸收体和一个微流体水容器组成。测量系统的构造使得热量计在热补偿模式下运行，其中吸收器的温度变化与吸收的能量成正比。用电加热和可见光源检查热补偿量热仪的可操作性。通过测量伽玛刀小辐射场的吸收剂量，成功证明了微流控芯片热量计应用于医用辐射传感器的可行性。