Phosphorescent Ir(III) complexes have attracted abundant attention in biomedical research due to their wide ranging properties and organelle specific intracellular imaging. Various types of Ir (III) complexes have been synthesized for visualization and monitoring of subcellular organelles and diagnosis of cancer. The aim of this review is to evaluate the progress of the phosphorescent Ir(III) complexes in bioimaging applications. We intend to highlight the use of Ir(III) complexes for staining the subcellular organelles, providing phosphorescence lifetime imaging microscopy, two photon and hypoxic tumor bioimaging.

中文翻译：

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磷化Ir（III）配合物作为生物医学分子成像的细胞染色剂

磷光的Ir（III）配合物由于其广泛的特性和细胞器特异的细胞内成像技术，在生物医学研究中引起了广泛的关注。已合成了各种类型的Ir（III）配合物，用于可视化和监视亚细胞器以及诊断癌症。这篇综述的目的是评估生物成像应用中的磷光Ir（III）配合物的进展。我们打算强调使用Ir（III）配合物对亚细胞器进行染色，提供磷光寿命成像显微镜，两个光子和低氧肿瘤生物成像。