Background Post-traumatic stress symptoms can occur in patients with medical illness. During the Middle East Respiratory Syndrome (MERS) outbreak in South Korea in 2015, some dialysis patients in three centers who were incidentally exposed to patients or medical staff with confirmed MERS-CoV infection were isolated to interrupt the spread of the infection. We aimed to investigate post-traumatic stress symptoms and risk factors among these patients. Materials and methods In total, 116 hemodialysis (HD) patients in contact with MERS-CoV-confirmed subjects were isolated using three strategies, namely, single room isolation, cohort isolation, and self-quarantine. We used the Impact of Event Scale-Revised-Korean (IES-R-K) to examine post-traumatic stress symptoms at 12 months after the isolation period. Results Of the 116 HD patients, 27 were lost to follow-up. Of the 89 patients, 67 (75.3%) completed the questionnaires. Single room isolation was used on 40 (58.8%) of the patients, cohort isolation on 20 (29.4%), and self-imposed quarantine on 8 (11.8%). In total, 17.9% of participants (n = 12) reported post-traumatic stress symptoms exceeding the IES-R-K's cutoff point (≧18). Prevalence rates of IES-R-K ≧18 did not differ significantly according to isolation method. However, isolation duration was linearly associated with the IES-R-K score (standardized β coefficient - 0.272, P = 0.026). Scores in Avoidance, Emotional numbing and Dissociation subscale were higher in patients with longer isolation period. Conclusion MERS was a traumatic experience for quarantined HD patients. IES-R-K scores were not significantly different by isolation methods. However, short isolation was associated with post-traumatic stress symptoms.

中文翻译：

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暴露于 MERS-CoV 的血液透析患者的创伤后应激症状。

背景 患有内科疾病的患者可能会出现创伤后应激症状。2015年韩国爆发中东呼吸综合征（MERS）期间，三个中心的部分透析患者因偶然接触到确诊为中东呼吸综合征冠状病毒的患者或医务人员而被隔离，以阻断感染的传播。我们旨在调查这些患者的创伤后应激症状和危险因素。材料与方法 共有 116 名与 MERS-CoV 确诊对象接触的血液透析（HD）患者采用单间隔离、队列隔离和自我隔离三种策略进行隔离。我们使用事件量表 - 修订韩语 (IES-RK) 的影响来检查隔离期后 12 个月的创伤后应激症状。结果 116 名 HD 患者中，27 人失访。在 89 名患者中，67 名（75.3%）完成了问卷调查。40 名（58.8%）患者使用单间隔离，20 名（29.4%）使用队列隔离，8 名（11.8%）使用自我隔离。总共有 17.9% 的参与者 (n = 12) 报告了超过 IES-RK 截止点 (≥18) 的创伤后应激症状。根据隔离方法，IES-RK≥18的患病率没有显着差异。然而，隔离持续时间与 IES-RK 评分呈线性相关（标准化 β 系数 - 0.272，P = 0.026）。在隔离期较长的患者中，回避、情绪麻木和分离分量表的得分较高。结论 MERS 对隔离的 HD 患者来说是一次创伤性经历。通过隔离方法，IES-RK 分数没有显着差异。然而，