Adolescent and young adult gliomas are recently being studied as a distinct group and molecular alterations of oligodendroglioma in this group are not well defined. Few studies conducted on adolescent oligodendroglioma so far have found low frequencies of IDH mutations and 1p/19q co-deletion, which are the hallmark genetic alterations seen in adult oligodendroglioma. In this case report, we demonstrate presence of rare IDH2 mutation and 1p/19q co-deletion in an adolescent oligodendroglioma.

中文翻译：

---

1p / 19q共缺失的青少年少突胶质细胞瘤IDH2突变罕见发生：一例病例报告。

青少年和成人胶质瘤最近被作为一个独立的研究对象，该组中少突胶质细胞瘤的分子改变尚不明确。迄今为止，对青春期少突胶质细胞瘤进行的研究很少，发现IDH突变和1p / 19q共缺失的频率较低，这是成人少突胶质细胞瘤的标志性遗传改变。在此病例报告中，我们证明了青少年少突胶质细胞瘤中存在罕见的IDH2突变和1p / 19q共缺失。