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Onchocerciasis dynamics: modelling the effects of treatment, education and vector control.
Journal of Biological Dynamics ( IF 1.8 ) Pub Date : 2020-04-08 , DOI: 10.1080/17513758.2020.1745306
Asha Hassan 1 , Nyimvua Shaban 1
Affiliation  

A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ivermectin drugs. Also, larviciding and trapping strategies are implemented in the vector population with the aim of controlling population growth of black flies. We fit the model to the data to check the suitability of the model. Expressions are derived for the influence on the reproduction numbers of these strategies. Numerical results show that the dynamics of onchocerciasis and the growth of black flies are best controlled when the four strategies are implemented simultaneously. Also, the results suggest that for the elimination of the disease in the society there is a need for finding another drug which will be implemented to ineligible human as well as killing the adult worms instead of ivermectin.

中文翻译:

盘尾丝虫病动力学:模拟治疗,教育和病媒控制的效果。

在根据疾病状况划分为多个区隔的社区中考虑了盘尾丝虫病动态的确定性模型。在使用伊维菌素药物进行大规模治疗期间,在社区中提供公共卫生教育。另外,在媒介种群中实施了杀幼虫和诱捕策略,目的是控制黑蝇的种群增长。我们将模型与数据拟合以检查模型的适用性。得出表达式对这些策略的复制数量的影响。数值结果表明,当同时实施这四种策略时,盘尾丝虫病的动力学和黑蝇的生长受到最佳控制。也,
更新日期:2020-04-08
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