Quantitative disease resistance (QDR) is a conserved form of plant immunity that limits infections caused by a broad range of pathogens. QDR has a complex genetic determinism. The extent to which molecular components of the QDR response vary across plant species remains elusive. The fungal pathogen Sclerotinia sclerotiorum, causal agent of white mold diseases on hundreds of plant species, triggers QDR in host populations. To document the diversity of local responses to S. sclerotiorum at the molecular level, we analyzed the complete transcriptomes of six species spanning the Pentapetalae (Phaseolus vulgaris, Ricinus communis, Arabidopsis [Arabidopsis thaliana], Helianthus annuus, Solanum lycopersicum, and Beta vulgaris) inoculated with the same strain of S. sclerotiorum. About one-third of plant transcriptomes responded locally to S. sclerotiorum, including a high proportion of broadly conserved genes showing frequent regulatory divergence at the interspecific level. Evolutionary inferences suggested a trend toward the acquisition of gene induction relatively recently in several lineages. Focusing on a group of ABCG transporters, we propose that exaptation by regulatory divergence contributed to the evolution of QDR. This evolutionary scenario has implications for understanding the QDR spectrum and durability. Our work provides resources for functional studies of gene regulation and QDR molecular mechanisms across the Pentapetalae.

定量抗病性（QDR）是植物免疫力的一种保守形式，可限制由多种病原体引起的感染。QDR具有复杂的遗传决定论。QDR反应的分子成分在不同植物物种之间变化的程度仍然难以捉摸。真菌病原菌核盘菌（Sclerotonia sclerotiorum）是数百种植物上白色霉菌病的致病因子，可触发宿主种群的QDR。为了证明局部反应的多样性菌核病在分子水平上，我们分析了6种横跨Pentapetalae完整转录（菜豆，蓖麻，拟南芥拟南芥]，向日葵，番茄茄和寻常的）接种了同一菌株的核盘菌。大约三分之一的植物转录组在本地对核盘菌有反应，包括高比例的广泛保守的基因，在种间水平上显示出频繁的调节差异。进化论的推论表明，相对较近的几个家族而言，获得基因诱导的趋势。我们着眼于一组ABCG转运蛋白，我们认为监管差异导致的免除对QDR的发展做出了贡献。这种进化方案对于理解QDR频谱和耐久性具有影响。我们的工作为整个五瓣纲的基因调控和QDR分子机制的功能研究提供资源。