Oligometastatic disease (OMD) is generally defined as a stage of clinically or radiographically demonstrated metastatic disease limited in total disease burden and without rapid spread. Interventional oncology performs local therapies for primary and metastatic cancers, including OMD. Interventional oncology treatments can be pursued both as definitive therapy and for palliative purposes. Applied to OMD, these interventions can offer patients a decreasing overall tumor burden, minimizing cancer morbidity, and early evidence suggests a survival benefit. Here, we discuss the range of interventional oncology treatments, including ablation, chemoembolization, radioembolization, and irreversible electroporation. We describe the rationale for their application to OMD and discuss future directions for research.

中文翻译：

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卵转移性疾病和介入肿瘤学：基本原理和研究方向。

少转移性疾病（OMD）通常定义为临床或放射学证明的转移性疾病，其总疾病负担有限且没有迅速扩散的阶段。介入肿瘤学对包括OMD在内的原发性和转移性癌症进行局部治疗。介入性肿瘤治疗既可以作为最终治疗也可以用于姑息治疗。将这些干预措施应用于OMD，可以为患者减少总体肿瘤负担，最大程度地降低癌症的发病率，而且早期证据表明可以提高生存率。在这里，我们讨论了介入肿瘤治疗的范围，包括消融，化学栓塞，放射栓塞，以及不可逆的电穿孔。我们描述了将其应用于OMD的原理，并讨论了未来的研究方向。