Fueling clonal dominance through TRAFficking of NF-κB signaling.,Nature Immunology

当前位置： X-MOL 学术 › Nat. Immunol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Fueling clonal dominance through TRAFficking of NF-κB signaling.
Nature Immunology ( IF 27.7 ) Pub Date : 2020-05-01 , DOI: 10.1038/s41590-020-0662-0
Koki Ueda _{1,

2} , Rajni Kumari _{1,

2} , Ulrich Steidl _{1,

2,

3,

4}

Affiliation

Activation of TLR–TRAF6 signaling by chronic inflammation in myelodysplastic syndromes increases the competitive advantage of HSPCs harboring MDS mutations through the upregulation of the ubiquitin-modifying enzyme A20 and a switch from canonical to non-canonical NF-κB signaling.

中文翻译：