Lithium is the gold standard treatment for bipolar disorders yet remains underutilized. Concerns among both patients and prescribing clinicians about Lithium’s narrow therapeutic index and potential for toxicity, necessitating blood level monitoring, is well documented. So too are serious long‐term side effects, for which psychiatrists must be ever vigilant and adequately trained to both prevent and mitigate, particularly in patients for whom Lithium has facilitated optimal functional recovery. This key aspect of treatment requires time intensive coordination of care and collaboration in health care systems that may not facilitate such training and educational efforts. Well marketed atypical antipsychotics seem, in comparison, a less convoluted treatment option.

中文翻译：

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解决双相情感障碍中持续的锂利用不足危机的三项建议。

锂是双相情感障碍的金标准治疗方法，但仍未得到充分利用。充分记录了患者和处方医生对锂的狭窄治疗指数和潜在毒性的担忧，这需要对血药水平进行监测。严重的长期副作用也是如此，精神科医生必须对此保持警惕，并接受充分的培训以预防和缓解，尤其是在锂促成最佳功能恢复的患者中。治疗的这一关键方面需要在医疗体系中花费大量时间进行护理协调和协作，这可能无法促进此类培训和教育工作。相比之下，销售良好的非典型抗精神病药似乎是一种不那么复杂的治疗选择。