A 0D/2D (0-dimensional/2-dimensional) nanostructure was designed by self-assembly of N-C QDs and carboxylated g-C3N4 nanosheets and used as a fluorescence resonance energy transfer (FRET) fluorescent sensor. The N-C QDs/g-C3N4 nanosheets were synthesized via the amino group on the N-C QD surface and the -COOH of the carboxylated g-C3N4 nanosheets. The mechanism of detection of metronidazole (MNZ) by N-C QDs/g-C3N4 nanocomposites is based on FRET between negatively charged N-QDs and positively charged carboxylated g-C3N4 nanoparticles. N-C QDs/g-C3N4 nanostructures displayed good responses for the detection of MNZ at normal temperature and pressure. The decrease in the fluorescence intensity showed a good linear relationship to MNZ concentration within 0-2.6 × 10-5 mol/L, and the detection limit was 0.66 μM. The novel FRET sensor will have a great potential in clinical analysis and biological studies.

中文翻译：

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通过 FRET 机制通过 0D/2D NC QDs/g-C3N4 纳米复合材料自组装对甲硝唑进行高选择性检测。


通过NC QD和羧化g-C3N4纳米片的自组装设计了0D/2D（0维/2维）纳米结构，并将其用作荧光共振能量转移（FRET）荧光传感器。通过NC QD表面的氨基和羧化g-C3N4纳米片的-COOH合成了NC QDs/g-C3N4纳米片。 NC QD/g-C3N4 纳米复合材料检测甲硝唑 (MNZ) 的机制基于带负电的 N-QD 和带正电的羧化 g-C3N4 纳米颗粒之间的 FRET。 NC QDs/g-C3N4 纳米结构在常温常压下对 MNZ 的检测表现出良好的响应。荧光强度的降低与MNZ浓度在0-2.6×10-5 mol/L范围内呈良好的线性关系，检测限为0.66 μM。新型FRET传感器将在临床分析和生物学研究中具有巨大的潜力。