Comprehensive two-dimensional liquid chromatography represents a valuable and powerful tool for the analysis of very complex samples. This review article illustrates how the coupling of two single LC “orthogonal” separations can be of valid aid for ensuring a deep chemical investigations of foods and food products. Specifically, in the first part, considerations about method optimization and novel modulation interfaces are reported whereas in the second part selected applications to polyphenols, lipids and carotenoids in various real-world samples are reported and discussed.

中文翻译：

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全面的二维液相色谱法是分析食品和食品的有力工具

全面的二维液相色谱代表了非常复杂的样品分析的宝贵而强大的工具。这篇评论文章阐述了如何将两个单个LC“正交”分离相结合可以有效地确保对食品和食品进行深入的化学研究。具体而言，在第一部分中，报告了有关方法优化和新型调制接口的考虑，而在第二部分中，则报告并讨论了在各种现实世界样本中对多酚，脂质和类胡萝卜素的选定应用。