Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous amounts of economic losses to the swine industry for more than three decades, but its control is still unsatisfactory. A significant amount of information is available for host cell-virus interactions during infection, and it is evident that PRRSV has evolved to equip various strategies to disrupt the host antiviral system and provide favorable conditions for survival. The current study reviews viral strategies for modulations of cellular processes including innate immunity, apoptosis, microRNAs, inflammatory cytokines, and other cellular pathways.

中文翻译：

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PRRSV发病机理和宿主对感染的反应的分子和细胞机制。

猪繁殖与呼吸综合症病毒（PRRSV）在过去的三十多年中给养猪业造成了巨大的经济损失，但其控制仍然不尽人意。大量信息可用于感染期间宿主细胞与病毒的相互作用，而且很明显PRRSV已进化为配备各种策略来破坏宿主抗病毒系统并为生存提供有利条件。本研究综述了病毒调节细胞过程的策略，包括先天免疫，细胞凋亡，microRNA，炎性细胞因子和其他细胞途径。