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In silico trials of food digestion and absorption: how far are we?
Current Opinion in Food Science ( IF 8.9 ) Pub Date : 2020-04-18 , DOI: 10.1016/j.cofs.2020.04.006
Steven Le Feunteun , Alan Robert Mackie , Didier Dupont

In recent years, experimental research on the mechanisms of food digestion in the gastrointestinal tract has strengthened our knowledge on the effect of food on human health. A number of mathematical models have been proposed to rationalize our understanding on the related mechanisms. One common suggestion is that in silico models could be interconnected and used in the future to predict the effect of food systems (liquid or solid, inner microstructure, state of nutrients…) on various metabolic responses. This paper aims to provide a brief overview of the latest developments in this young but promising field of research.



中文翻译:

在计算机上进行的食物消化吸收实验:我们走了多远?

近年来,有关胃肠道食物消化机制的实验研究加强了我们对食物对人体健康影响的认识。已经提出了许多数学模型来合理化我们对相关机制的理解。一个普遍的建议是,计算机模拟模型可以相互关联并在将来用于预测食物系统(液体或固体,内部微结构,营养状况等)对各种代谢反应的影响。本文旨在简要概述这一年轻但有希望的研究领域的最新发展。

更新日期:2020-04-18
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