The chromatic detecting system for neomycin was fabricated using the diacetylene compound. Three kinds of the diacetylene compounds were used in this study. Among these compounds, only the compound which has an amino group showed the chromatic activity for the aminoglycoside antibiotics. Because this system did not get the response to glucose and glucosamine which get the similar molecular structure with aminoglycoside antibiotics, I can say that both more than 3 glucose units and amino functional group were needed to show the chromatic activity. The order of the detecting ability to the aminoglycoside antibiotics was neomycin > gentamycin ≫ streptomycin in which this order agrees with the order of increasing the number of the amine functional group. The fabrication of the chromatic detecting system for neomycin was accomplished without the difficult synthesis of complicated detecting unit.

中文翻译：

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氨基官能化聚二乙炔检测新霉素

使用二乙炔化合物制造了新霉素的彩色检测系统。本研究中使用了三种乙炔化合物。这些化合物中，仅具有氨基的化合物对氨基糖苷类抗生素显示出显色活性。因为该系统对氨基糖苷类抗生素的分子结构相似的葡萄糖和氨基葡萄糖没有反应，所以可以说需要三个以上的葡萄糖单元和氨基官能团来显示其显色活性。对氨基糖苷类抗生素的检测能力顺序为新霉素>庆大霉素y链霉素，其顺序与增加胺官能团数的顺序一致。