BACKGROUND In 2013, an outbreak of edema disease in a population of wild boars (Sus scrofa) took place. This was the first described case as reported worldwide. An enterotoxigenic Escherichia coli (presenting the Stx2e and F18 virulence factors) is the main pathogen for this disease in wild boar. The alpha-1-fucosyltransferase gene (FUT1) has been identified as the gene regulating the expression of the receptor for E. coli stx2e F18 bacteria in domestic pigs affected by the disease. The genotypic frequencies of the FUT1 gene in European wild boars have not yet been investigated. The genotypes of wild boars for this gene were determined in four French departments with or without edema diseases cases. RESULTS All of the wild boars analyzed had a genotype susceptible to the disease (GG or AG). The recessive, resistant A allele was found for the first time in wild boars, but in a very small proportion of individuals (7/222). No statistical differences were found between healthy hunted wild boars versus wild boars found dead by edema disease or among the four French departments. CONCLUSIONS These results suggest that further mortality due to edema disease remains possible in wild boars in France.

中文翻译：

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法国几个野猪 (Sus scrofa) 群体中 α-1-岩藻糖基转移酶 (FUT1) 基因的多态性与水肿病有关。


背景技术2013年，野猪（Sus scrofa）群体爆发了水肿病。这是全球报道的首例描述病例。产肠毒素大肠杆菌（具有 Stx2e 和 F18 毒力因子）是野猪这种疾病的主要病原体。 α-1-岩藻糖基转移酶基因 (FUT1) 已被确定为调节受该疾病影响的家猪中大肠杆菌 stx2e F18 细菌受体表达的基因。欧洲野猪中 FUT1 基因的基因型频率尚未得到研究。在有或没有水肿疾病病例的法国四个省确定了野猪的该基因的基因型。结果 所有分析的野猪都具有对该疾病敏感的基因型（GG 或 AG）。隐性抗性 A 等位基因首次在野猪中发现，但只在极少数个体中发现 (7/222)。健康的猎杀野猪与因水肿病死亡的野猪之间或法国四个省之间没有发现统计差异。结论 这些结果表明，法国野猪仍有可能因水肿病而进一步死亡。