Benign convulsions with gastroenteritis are characterized by a cluster of seizures. Sodium channel blockers are efficacious. We prescribed lacosamide, a new channel blocker, for five patients. Patient age ranged from 17 to 33 months; all five experienced 1-4 generalized convulsions persisting for 30-120 s. One patient exhibited a transient splenial lesion on head magnetic resonance imaging. All received one dose (2 mg/kg) of lacosamide. The convulsions ceased, and no adverse drug effect was noted. A single dose of lacosamide was effective and well-tolerated in five patients with benign convulsions with gastroenteritis.

中文翻译：

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拉考沙胺治疗胃肠炎良性惊厥的试验

肠胃炎的良性抽搐的特征是一系列癫痫发作。钠通道阻滞剂有效。我们为五名患者开了拉考沙胺，一种新的通道阻滞剂。患者年龄介于 17 至 33 个月之间；所有五人都经历了 1-4 次持续 30-120 秒的全身抽搐。一名患者在头部磁共振成像上表现出一过性脾脏病变。所有人都接受了一剂拉科酰胺（2 mg/kg）。抽搐停止了，没有注意到药物不良反应。单剂量拉考沙胺对 5 名患有胃肠炎的良性惊厥患者有效且耐受性良好。