Trichophyton rubrum is the most common aetiological agent of human dermatophytoses. These infections mainly occur in keratinised layers such as skin, hair and nails because the fungus uses keratin as a nutrient source. Fluconazole and amphotericin are antifungal agents most commonly used to treat dermatophytoses and acts on cell membrane ergosterol. Despite the clinical importance of T rubrum, the mechanisms underlying the fungal‐host relationship have not yet been clarified. Tandem repeats (TRs) are short DNA sequences that are involved in a variety of adaptive functions, including the process of fungal infection. It is known that the larger the number of TRs in the genome, the greater the capacity of cell‐cell junction and surface adhesion, especially when these repeats are present in regions encoding cell surface proteins.

中文翻译：

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红色毛癣菌中含有参与真菌-宿主相互作用和抗真菌反应的串联重复模式基因的表达

红色毛癣菌是人类皮肤癣菌病最常见的病原体。这些感染主要发生在角化层，如皮肤、头发和指甲，因为真菌使用角蛋白作为营养来源。氟康唑和两性霉素是最常用于治疗皮肤癣菌病和作用于细胞膜麦角甾醇的抗真菌剂。尽管红色毛癣菌具有临床重要性，但真菌-宿主关系的潜在机制尚未阐明。串联重复序列 (TR) 是短 DNA 序列，涉及多种适应性功能，包括真菌感染过程。众所周知，基因组中 TR 的数量越多，细胞-细胞连接和表面粘附的能力就越大，尤其是当这些重复存在于编码细胞表面蛋白的区域时。