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Improvement of sexual functioning during treatment of MDD with adjunctive pimavanserin: A secondary analysis.
Depression and Anxiety ( IF 4.7 ) Pub Date : 2020-04-17 , DOI: 10.1002/da.23017
Marlene P Freeman 1 , Maurizio Fava 1 , Bryan Dirks 2 , Manish K Jha 3 , George I Papakostas 1 , Richard C Shelton 4 , Michael E Thase 5 , Madhukar H Trivedi 6 , Keith Liu 2 , Srdjan Stankovic 2
Affiliation  

Sexual dysfunction is common among patients with major depressive disorder (MDD). In the CLARITY study, the safety and efficacy of adjunctive pimavanserin, an inverse agonist at 5‐HT2A receptors, were demonstrated when added to existing treatment for MDD. This analysis provides a detailed assessment of the effects of pimavanserin on sexual function from the CLARITY study.

中文翻译:

辅助皮万古林治疗MDD期间性功能的改善:次要分析。

重度抑郁症(MDD)患者常见性功能障碍。在CLARITY研究中,在现有的MDD治疗药物中加入了辅助的pimavanserin(5-HT 2A受体反向激动剂)的安全性和有效性。这项分析通过CLARITY研究提供了对匹马西林对性功能的影响的详细评估。
更新日期:2020-04-17
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