Bipolar disorder (BD) has been associated with abnormal reward functioning including pleasure‐seeking and impulsivity. Here we sought to clarify whether these changes can be attributed to abnormalities in the neural processing of reward valuation or error prediction. Moreover, we tested whether abnormalities in these processes are associated with familial vulnerability to BD.

中文翻译：

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在最近诊断出的躁郁症患者及其未患病的亲属中，奖励预测错误的前额叶皮层处理异常。

躁郁症（BD）与奖励功能异常有关，包括愉悦和冲动。在这里，我们试图澄清这些变化是否可以归因于奖励评估或错误预测的神经处理中的异常。此外，我们测试了这些过程中的异常是否与家族性BD易感性有关。