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Lipid-based mesophases as matrices for nanoscale reactions.
Nanoscale Horizons ( IF 8.0 ) Pub Date : 2020-04-16 , DOI: 10.1039/d0nh00079e
Livia Salvati Manni 1 , Wye-Khay Fong , Raffaele Mezzenga
Affiliation  

Lipidic mesophases are versatile bioorganic materials that have been effectively employed as nanoscale matrices for membrane protein crystallization, drug delivery and as food emulsifiers over the last 30 years. In this review, the focus is upon studies that have employed non-lamellar lipid mesophases as matrices for organic, inorganic and enzymatic reactions. The ability of lipidic mesophases to incorporate hydrophilic, amphiphilic and hydrophobic molecules, together with the high interfacial area of the lipidic cubic and inverse hexagonal phases has been exploited in heterogeneous catalysis as well as for enzyme immobilization. The unique nanostructure of these mesophases is the driving force behind their ability to act as templates for synthesis, resulting in the creation of highly ordered polymeric and inorganic materials with complex geometries.

中文翻译:

基于脂质的中间相作为纳米级反应的基质。

脂质中间相是一种通用的生物有机材料,在过去的30年中已被有效地用作纳米级基质,用于膜蛋白结晶,药物输送和食品乳化剂。在这篇综述中,重点是将非层状脂质中间相用作有机,无机和酶促反应基质的研究。脂族中间相结合亲水,两亲和疏水分子的能力,以及脂族立方相和反六方相的高界面面积,已在非均相催化以及酶固定中得到了利用。这些中间相的独特纳米结构是其充当合成模板的能力背后的驱动力,
更新日期:2020-04-16
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