Low‐elevation species can migrate toward higher elevations to survive in a warming world. However, animals’ responses to hypoxia when migrating to high elevations have rarely been addressed. To identify the response of low‐elevation lizards to high‐elevation hypoxia, we collected field body temperatures (T_fb) and operative temperatures (T_e) of lizards (Eremias argus) from a low‐elevation population (1036 m) and a high‐elevation population (2036 m), and then determined adult thermal physiology, embryonic development, and hatchling phenotypes after acclimating low‐elevation lizards and incubating their eggs in conditions mimicking the low‐elevation oxygen condition (18.5% O₂) and high‐elevation oxygen (hypoxic) condition (16.5% O₂). Our study revealed that T_fb and T_e were higher for the low‐elevation population compared to the high‐elevation population. We also found adults from low elevation acclimated to hypoxia preferred lower body temperatures, but did not show changes in locomotor performance or growth. In addition, hypoxia did not affect embryonic development (hatching time and success) or hatchling phenotypes (body size and locomotor performance). These results suggest that adult lizards from low elevations can respond to hypoxia‐induced stress when migrating to high elevations by behaviorally thermoregulating to lower body temperatures in order to sustain normal functions. Similarly, low‐elevation embryos can develop normally (with unchanged hatching success and offspring phenotypes) under the high‐elevation hypoxic condition. This study highlights that low‐elevation populations of a species that inhabits a range of elevations can buffer the impact of high‐elevation hypoxic conditions to some degree and thus attain similar fitness to the source population.

中文翻译：

---

胚胎和胚胎后对低海拔蜥蜴的高海拔缺氧的反应。

低海拔物种可以向更高海拔迁移，以在变暖的世界中生存。然而，动物迁徙到高海拔时对缺氧的反应很少得到解决。为了确定低海拔蜥蜴对高海拔缺氧的反应，我们从低海拔人群（1036 m）和高海拔人群中收集了蜥蜴（Eremias argus）的野外体温（T _fb）和操作温度（T _e）。高海拔种群（2036 m），然后在适应低海拔蜥蜴并在类似于低海拔氧气条件（18.5％O _2）的条件下孵化后确定成年动物的热生理，胚胎发育和孵化表型）和高氧（低氧）条件（16.5％O ₂）。我们的研究表明T _fb和T _e低海拔人群比高海拔人群更高。我们还发现，从低海拔适应低氧的成年人更喜欢较低的体温，但运动能力或生长没有变化。另外，低氧不会影响胚胎发育（孵化时间和成功）或孵化表型（体型和运动能力）。这些结果表明，低海拔的成年蜥蜴在迁移到高海拔时，可以通过行为调节体温来降低体温，以维持正常功能，从而应对缺氧引起的压力。同样，在高海拔缺氧条件下，低海拔胚胎可以正常发育（孵化成功率和后代表型不变）。