Bulimia nervosa (BN) and binge eating disorder (BED) are psychiatric conditions marked by emotional disorders managed through the ingestion of great amount of food, with consequent vomiting for avoiding weight gain. Such behavioral habits are dysfunctional and severely impact both psychological and physical health, also compromising neurobiological processes. In the present review, we focus on recent neuroimaging findings (2010-2019) that provide insight into the neural bases of BN and BED. We describe the role of different neuroimaging techniques (magnetic resonance imaging, both structural and functional, positron emission tomography, single-photon emission computerized tomography, electroencephalography and magnetoencephalography) in the delineation of pathophysiological aspects of BN and BED. Results highlight the main involvement of the frontal system and its relationships with temporal areas for reward and self-regulatory processes modulation. The network that regulates food-stimuli control seems to be widespread across the brain, catching the insula, precentral gyrus, frontal cortex and extending until the visual cortex for processing of body image. These results demonstrate diffuse brain vulnerability associated with BN and BED and can confirm that symptomatology maintenance results from several neurostructural and neurofunctional alterations.

中文翻译：

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神经性贪食症和暴食症多模式神经影像学的广谱综述

神经性贪食症 (BN) 和暴食症 (BED) 是精神疾病，其特征是通过摄入大量食物来控制情绪障碍，随后呕吐以避免体重增加。这种行为习惯是功能失调的，严重影响心理和身体健康，还会损害神经生物学过程。在本综述中，我们关注最近的神经影像学发现（2010-2019），这些发现提供了对 BN 和 BED 神经基础的深入了解。我们描述了不同的神经影像技术（磁共振成像，结构和功能，正电子发射断层扫描，单光子发射计算机断层扫描，脑电图和脑磁图）在描述 BN 和 BED 的病理生理学方面的作用。结果突出了额叶系统的主要参与及其与奖励和自我调节过程调制的时间区域的关系。调节食物刺激控制的网络似乎遍布整个大脑，捕捉脑岛、中央前回、额叶皮层并延伸至视觉皮层以处理身体图像。这些结果证明了与 BN 和 BED 相关的弥漫性大脑脆弱性，并且可以确认症状维持是由几种神经结构和神经功能改变引起的。额叶皮层并延伸至视觉皮层，用于处理身体形象。这些结果证明了与 BN 和 BED 相关的弥漫性大脑脆弱性，并且可以确认症状维持是由几种神经结构和神经功能改变引起的。额叶皮层并延伸至视觉皮层，用于处理身体形象。这些结果证明了与 BN 和 BED 相关的弥漫性大脑脆弱性，并且可以确认症状维持是由几种神经结构和神经功能改变引起的。