Background

The appendix and ovaries are rarely involved simultaneously in malignancies. The decision to perform an ovarian biopsy or a surgical resection in young patients can be challenging without sufficient clinical information.

Case

We describe an 11-year-old girl with bilateral ovarian masses, an enlarged appendix, associated pleural effusion, and ascites. Appendectomy and biopsy of the bilateral ovarian masses led to a diagnosis of aggressive B-cell non-Hodgkin lymphoma. The patient was treated with chemotherapy, which achieved complete remission and bilateral ovarian preservation.

Summary and Conclusion

If ovarian involvement in malignant lymphoma is suspected, diagnostic methods should spare the ovary and prevent a loss of fertility. To evaluate for possible chemotherapy-induced ovarian damage, including infertility and premature menopause, an interdisciplinary approach is needed for the long-term follow-up of adolescent girls.

中文翻译：

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涉及一名11岁女孩的附录和双侧卵巢的侵袭性B细胞淋巴瘤。

背景

阑尾和卵巢很少同时参与恶性肿瘤。没有足够的临床信息，对年轻患者进行卵巢活检或手术切除的决定可能具有挑战性。

案件

我们描述了一个11岁的女孩，有双侧卵巢包块，阑尾增大，相关的胸腔积液和腹水。双侧卵巢肿块的阑尾切除术和活检可诊断为侵袭性B细胞非霍奇金淋巴瘤。该患者接受化学疗法治疗，完全缓解，双侧卵巢得以保存。

总结与结论

如果怀疑卵巢受累于恶性淋巴瘤，则诊断方法应使卵巢免受伤害并防止生育力下降。为了评估可能由化学疗法引起的卵巢损害，包括不育和更年期提前，需要对青少年女孩进行长期随访的跨学科方法。