The immune and physiological responses of mud crab (Scylla paramamosain) under air exposure were studied. The results showed that air exposure increased plasma activities of AST, ALT, ALP. There was a significant increase in glucose (GLU) and malondialdehyde (MDA) levels after air exposure. The transcript levels of SOD, CAT, HSP90, HSP70, p53, and hypoxia-inducible factor-1 (HIF-1) were induced by air exposure. Furthermore, caspase-3 transcript significantly increased at 48 and 72 h, while it significantly decreased at 96 h and 120 h under air exposure. These results suggested that oxidative stress occurred in the prolonged period of air exposure. HIF-1 and p53 signaling pathways played an important role under air exposure.

中文翻译：

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空气暴露下的泥蟹（Scylla paramamosain）的免疫和生理反应。

研究了暴露在空气中的泥蟹（Scylla paramamosain）的免疫和生理反应。结果表明，暴露于空气中会增加AST，ALT，ALP的血浆活性。暴露于空气后，葡萄糖（GLU）和丙二醛（MDA）含量显着增加。暴露于空气可诱导SOD，CAT，HSP90，HSP70，p53和缺氧诱导因子-1（HIF-1）的转录水平。此外，在暴露于空气的情况下，caspase-3转录物在48和72 h显着增加，而在96 h和120 h显着降低。这些结果表明氧化应激在长时间暴露于空气中发生。HIF-1和p53信号通路在空气暴露下起着重要作用。