Steroidal glycosides (1-21), including eight new spirostanol glycosides (1-8) and a new cholestane glycoside (9), were isolated from the bulbs of Lilium speciosum. The structures of the new compounds were determined based on spectroscopic data analysis and hydrolytic cleavage reactions. The isolated compounds and their aglycones (1a, 8a, and 9a) were evaluated for their cytotoxicity against HL-60 human acute promyelocytic leukemia cells and A549 human lung carcinoma cells. Compounds 12 and 21 exhibited moderate cytotoxic activity toward HL-60 and A549 cells, with IC₅₀ values of 6.9 μM and 5.1 μM against HL-60 cells, and 7.6 μM and 4.4 μM against A549 cells, respectively. Compound 20 only showed moderate cytotoxicity toward A549 cells, with an IC₅₀ value of 6.7 μM.

甾体糖苷（1 - 21），包括八个新spirostanol甙（1 - 8）和一个新的胆甾糖苷（9），从鳞茎分离鹿子百合。基于光谱数据分析和水解裂解反应确定了新化合物的结构。评价分离的化合物及其糖苷配基（1a，8a和9a）对HL-60人急性早幼粒细胞白血病细胞和A549人肺癌细胞的细胞毒性。化合物12和21对HL-60和A549细胞具有中等的细胞毒活性，对HL-60细胞的IC ₅₀值分别为6.9μM和5.1μM，对A549细胞的IC ₅₀值分别为7.6μM和4.4μM。化合物20仅显示出对A549细胞的中等细胞毒性，IC ₅₀值为6.7μM。