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Bacterial cellulose micro-nano fibres for wound healing applications.
Biotechnology Advances ( IF 12.1 ) Pub Date : 2020-04-14 , DOI: 10.1016/j.biotechadv.2020.107549
Jubair Ahmed 1 , Merve Gultekinoglu 2 , Mohan Edirisinghe 1
Affiliation  

Bacterial cellulose (BC) is cellulose produced by a few limited species of bacteria in given conditions. BC has many remarkable properties such as its attractive mechanical properties, water uptake ability and biocompatibility which makes it a very desirable material to be used for wound healing. Inherently due to these important properties, the material is very resistant to easy processing and thus difficult to produce into useful entities. Additionally, being rate limited by the dependency on bacterial production, high yield is difficult to obtain and thus secondary material processing is sought after. In this review, BC is explained in terms of synthesis, structure and properties. These beneficial properties are directly related to the material's great potential in wound healing where it has also been trialled commercially but ultimately failed due to processing issues. However, more recently there has been increased frequency in scientific work relating to BC processing into hybrid polymeric fibres using common laboratory fibre forming techniques such as electrospinning and pressurised gyration. This paper summarises current progress in BC fibre manufacturing, its downfalls and also gives a future perspective on how the landscape should change to allow BC to be utilised in wound care in the current environment.



中文翻译:

用于伤口愈合的细菌纤维素微纳米纤维。

细菌纤维素(BC)是在给定条件下由少数几种细菌产生的纤维素。BC具有许多非凡的性能,例如其吸引人的机械性能,吸水能力和生物相容性,这使其成为用于伤口愈合的非常理想的材料。本质上由于这些重要特性,该材料非常易于加工,因此很难生产成有用的实体。另外,由于速率受细菌生产依赖性的限制,难以获得高产率,因此寻求二级材料加工。在这篇综述中,从合成,结构和性质方面解释了BC。这些有益的特性与材料的 在伤口愈合方面具有巨大潜力,该伤口也已经进行了商业试用,但由于加工问题最终失败了。然而,近来,与使用常规实验室纤维形成技术例如电纺和加压回转技术进行的BC加工成混合聚合物纤维有关的科学工作的频率已经增加。本文总结了BC纤维制造的最新进展,它的衰落,并就如何改变景观以使BC在当前环境下用于伤口护理提供了未来的看法。

更新日期:2020-04-14
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