Three new steroidal saponins, aspiletreins A–C (1–3), together with 2H-chromen-2-one (4), and α-tocopherol (5), were isolated from whole Aspidistra letreae plants collected in Vietnam. Their structures were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR, IR, and HRESIMS, and by comparison with the reported data in the literature. Compounds 1–3 exhibited moderate cytotoxicities against the LU-1, HeLa, MDA-MB-231, HepG2, and MKN-7 human cancer cell lines, with IC₅₀ values ranging from 7.69 ± 0.40 to 20.46 ± 3.11 µM.

中文翻译：

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来自 Aspidistra letreae 植物的三种新甾体皂苷及其细胞毒活性。


从越南收集的整个Aspidistra letreae植物中分离出三种新的甾体皂苷，aspiletreins A–C ( 1 – 3 )，以及 2 H -chromen-2-one ( 4 ) 和α -生育酚 ( 5 ) 。通过结合光谱分析（包括 1D 和 2D-​​NMR、IR 和 HRESIMS）并与文献中报告的数据进行比较，阐明了它们的结构。化合物1 – 3对 LU-1、HeLa、MDA-MB-231、HepG2 和 MKN-7 人类癌细胞系表现出中等的细胞毒性，IC ₅₀值范围为 7.69 ± 0.40 至 20.46 ± 3.11 µM。