Epidermal neural crest stem cell transplantation as a promising therapeutic strategy for ischemic stroke.,CNS Neuroscience & Therapeutics

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Epidermal neural crest stem cell transplantation as a promising therapeutic strategy for ischemic stroke.
CNS Neuroscience & Therapeutics ( IF 5.5 ) Pub Date : 2020-04-12 , DOI: 10.1111/cns.13370
Mohammad Saied Salehi ₁ , Sareh Pandamooz ₂ , Anahid Safari ₃ , Benjamin Jurek ₄ , Amin Tamadon ₅ , Mohammad Reza Namavar ₁ , Mehdi Dianatpour ₃ , Leila Dargahi ₂ , Negar Azarpira ₆ , Sadegh Fattahi ₇ , Seyed Mostafa Shid Moosavi ₈ , Somaye Keshavarz ₈ , Zahra Khodabandeh ₃ , Shahrokh Zare ₃ , Somayeh Nazari ₈ , Mojdeh Heidari ₆ , Sadegh Izadi ₁ , Maryam Poursadeghfard ₁ , Afshin Borhani-Haghighi ₁

Affiliation

Cell‐based therapy is considered as promising strategy to cure stroke. However, employing appropriate type of stem cell to fulfill many therapeutic needs of cerebral ischemia is still challenging. In this regard, the current study was designed to elucidate therapeutic potential of epidermal neural crest stem cells (EPI‐NCSCs) compared to bone marrow mesenchymal stem cells (BM‐MSCs) in rat model of ischemic stroke.

中文翻译：

表皮神经嵴干细胞移植作为缺血性中风的一种有前途的治疗策略。

基于细胞的治疗被认为是治愈中风的有希望的策略。然而，采用合适类型的干细胞来满足脑缺血的许多治疗需求仍然具有挑战性。在这方面，目前的研究旨在阐明表皮神经嵴干细胞 (EPI-NCSCs) 与骨髓间充质干细胞 (BM-MSCs) 在缺血性中风大鼠模型中的治疗潜力。

更新日期：2020-04-12

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