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The two-step task, avoidance, and OCD.
Journal of Neuroscience Research ( IF 2.9 ) Pub Date : 2020-04-13 , DOI: 10.1002/jnr.24594
Matthew A Geramita 1, 2, 3 , Eric A Yttri 2, 3 , Susanne E Ahmari 1, 3
Affiliation  

In this invited review, we argue for the need to determine whether appetitive and aversive behaviors, be they goal-directed or habitual, share overlapping neural circuitry. To motivate our argument, we first summarize what is currently known about the neural circuits governing aversive and appetitive behaviors by focusing first on the three hypothesized phases of avoidance learning, and then on goal-directed and habitual reward seeking. We then provide several reasons to believe that the neural circuits of appetitive and aversive instrumental behaviors are not completely overlapping. We next discuss an experimental strategy to determine the extent of overlap based on a new computational framework that improves the identification of goal-directed and habitual actions regardless of valence. Finally, we discuss recent work in obsessive-compulsive disorder that uses this computational framework to determine whether patients perform appetitive and aversive versions of the same task using the same behavioral strategies and neural circuits.

中文翻译:

两步任务,回避和强迫症。

在这篇受邀的评论中,我们认为需要确定食欲和厌恶行为,无论是目标导向的还是习惯性的,是否共享重叠的神经回路。为了激发我们的论点,我们首先通过首先关注回避学习的三个假设阶段,然后关注目标导向和习惯性奖励寻求,总结了目前对控制厌恶和食欲行为的神经回路的了解。然后我们提供了几个理由来相信食欲和厌恶工具行为的神经回路并不完全重叠。我们接下来讨论一种实验策略,以确定基于新计算框架的重叠程度,该框架改进了对目标导向和习惯性行为的识别,而不管效价如何。最后,
更新日期:2020-04-13
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