Nonclassical class I MHC-like molecules are ligands for several unconventional T cell populations. Recently, Le Nours et al. identified human γδ T cells recognising MHC-related protein-1 (MR1) via their T cell receptor (TCR). Also recognised by the αβ-TCR of mucosal associated invariant T cells, MR1 interacts with specific γδ-TCRs using strikingly diverse binding modes, suggesting fundamental differences in γδ T cell recognition.

中文翻译：

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MR1的γδTCR识别：适应翻转侧的生活。

非经典的I类MHC类分子是几种非常规T细胞群体的配体。最近，Le Nours等人。鉴定出通过其T细胞受体（TCR）识别MHC相关蛋白1（MR1）的人γδT细胞。MR1也被粘膜相关的恒定T细胞的αβ-TCR识别，它利用显着多样的结合模式与特定的γδ-TCR相互作用，这提示了γδT细胞识别的根本差异。