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Metabolic engineering strategies toward production of biofuels.
Current Opinion in Chemical Biology ( IF 6.9 ) Pub Date : 2020-04-13 , DOI: 10.1016/j.cbpa.2020.02.009
Kyeong Rok Choi 1 , Song Jiao 1 , Sang Yup Lee 2
Affiliation  

Exacerbation of climate change and air pollution around the world have emphasized the necessity of replacing fossil fuels with clean and sustainable energy. Metabolic engineering has provided strategies to engineer diverse organisms for the production of biofuels from renewable carbon sources. Although some of the processes are commercialized, there has been continued effort to produce advanced biofuels with higher efficiencies. In this article, metabolic engineering strategies recently exploited to enhance biofuel production and facilitate utilization of non-edible low-value carbon sources are reviewed. The strategies include engineering enzymes, exploiting new pathways, and systematically optimizing metabolism and fermentation processes, among others. In addition, metabolic and bioprocess engineering strategies to achieve competitiveness of current biofuel production systems compared with fossil fuels are discussed.

中文翻译:

生产生物燃料的代谢工程策略。

全球气候变化和空气污染的加剧强调了用清洁和可持续能源替代化石燃料的必要性。代谢工程提供了设计不同生物体以从可再生碳源生产生物燃料的策略。尽管其中一些工艺已商业化,但仍继续努力生产更高效的先进生物燃料。在本文中,回顾了最近用于提高生物燃料生产和促进非食用低价值碳源利用的代谢工程策略。这些策略包括工程酶、开发新途径以及系统地优化代谢和发酵过程等。此外,
更新日期:2020-04-13
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