AIM To compare the prevalence of mental disorders (MDs) in a cohort of children and adolescents with and without cerebral palsy (CP) and to explore whether there is an association between MDs and the Gross Motor Function Classification System (GMFCS) level. METHOD A register-linkage follow-up study of 10- to 16-year children with CP (identified in the Danish National Cerebral Palsy Registry, n = 893), and 2627 children without CP, matched by gender and age. Information on MDs was obtained from the National Patient Registry in Denmark and based on ICD-10-codes. Conditional logistic regression was performed in order to compare the prevalence of MDs. RESULTS The prevalence of MDs was significantly higher in children and adolescents with CP (22.4%, CI 19.8-25.2%) compared with controls (6.3%, CI 5.5-7.3%). Intellectual disability was statistically significantly associated with motor function (odds ratio (OR) 4.55, CI 2.81-7.36 for GMFCS levels IV-V compared to GMFCS level I), but there were no statistically significant association between motor function and autism spectrum disorders, ADHD or affective disorders. INTERPRETATION Our findings emphasize that follow-up of children with CP should include screening for both cognitive dysfunction and other mental disorders. The motor function does not predict the risk of other mental disorders than intellectual disability in children and adolescents with CP.

中文翻译：

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脑瘫儿童和青少年精神障碍患病率：丹麦全国随访研究

目的 比较一组患有和不患有脑瘫（CP）的儿童和青少年的精神障碍（MDs）患病率，并探讨 MDs 与大运动功能分类系统（GMFCS）水平之间是否存在关联。方法 对 10 至 16 岁患有 CP 的儿童（在丹麦国家脑性麻痹登记处确定，n = 893）和 2627 名无 CP 的儿童进行了一项注册连锁随访研究，按性别和年龄进行匹配。有关 MD 的信息来自丹麦的国家患者登记处，并基于 ICD-10 代码。进行条件逻辑回归以比较 MD 的患病率。结果 与对照组（6.3%，CI 5.5-7.3%）相比，患有 CP 的儿童和青少年的 MDs 患病率（22.4%，CI 19.8-25.2%）显着更高。智力障碍与运动功能有统计学显着相关性（与 GMFCS 水平 I 相比，GMFCS IV-V 水平的比值比 (OR) 4.55，CI 2.81-7.36），但运动功能与自闭症谱系障碍、ADHD 之间没有统计学显着关联或情感障碍。解释 我们的研究结果强调，对 CP 儿童的随访应包括筛查认知功能障碍和其他精神障碍。在患有脑瘫的儿童和青少年中，运动功能不能预测除智力障碍以外的其他精神障碍的风险。多动症或情感障碍。解释 我们的研究结果强调，对 CP 儿童的随访应包括筛查认知功能障碍和其他精神障碍。在患有脑瘫的儿童和青少年中，运动功能不能预测除智力障碍以外的其他精神障碍的风险。多动症或情感障碍。解释 我们的研究结果强调，对 CP 儿童的随访应包括筛查认知功能障碍和其他精神障碍。在患有脑瘫的儿童和青少年中，运动功能不能预测除智力障碍以外的其他精神障碍的风险。