Background

Aromatase inhibitors (AIs) are used for estrogen-modulated conditions. Some borderline ovarian tumors (BOT) express estrogen receptors. We present 2 cases of progression from mucinous cystadenoma to mucinous BOT (mBOT) after prior cystectomies in whom an AI was used with recurrence prevention.

Cases

Two patients underwent laparoscopic ovarian cystectomy for mucinous cystadenoma. Serial imaging demonstrated recurrent ovarian cysts for which both underwent fertility sparing surgery (FSS) with ovarian cystectomy for mBOT. Both patients were initiated on an AI and have been without recurrence.

Summary and Conclusion

BOT predominantly occur in reproductive aged females. FSS with cystectomy is an option, but recurrence occurs in 12-36% of cases. The use of AI in prevention of recurrent BOT shows promise, and more studies are needed to explore this treatment.

中文翻译：

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芳香酶抑制剂预防复发性粘液性交界性卵巢肿瘤。

背景

芳香酶抑制剂（AIs）用于雌激素调节性疾病。一些卵巢交界性肿瘤（BOT）表达雌激素受体。我们提出了2例先前的膀胱切除术后从粘液性囊腺瘤发展为粘液性BOT（mBOT）的病例，其中使用AI预防复发。

案例

两名患者因粘液性囊腺瘤接受了腹腔镜卵巢膀胱切除术。连续影像学检查显示复发性卵巢囊肿，均对其进行了保留生育手术（FSS）和卵巢囊肿切除术以治疗mBOT。两名患者均开始接受AI治疗，但均未复发。

总结与结论

BOT主要发生在育龄女性中。FSS膀胱切除术是一种选择，但复发的发生率在12-36％的病例中。使用AI预防复发性BOT已显示出希望，需要更多的研究来探索这种治疗方法。