Based on antimicrobial susceptibility test interpretive breakpoint criteria from Clinical and Laboratory Standards Institute and United States Committee on Antimicrobial Susceptibility Testing, cefazolin uncomplicated urinary tract infection (uUTI) surrogate breakpoints do not accurately predict cefadroxil or cephradine susceptibility when testing indicated Enterobacteriaceae species isolates. Hence, these two orally-administered cephalosporins (OC) are not equivalent spectrum substitutes for cephalexin or six other related OC agents for contemporary uUTI therapy.

中文翻译：

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头孢唑啉替代药敏性断点的重新分析，用作口服头孢菌素治疗简单尿路感染的指南：关于应用头孢羟氨苄的警告。

根据临床和实验室标准协会和美国抗菌药物敏感性试验委员会的抗菌药物敏感性试验解释性断点标准，当检测到肠杆菌科细菌分离物时，头孢唑啉无并发症尿路感染（uUTI）替代断点不能准确预测头孢氨苄或头孢拉定的敏感性。因此，这两种口服头孢菌素（OC）不能等效替代头孢氨苄或当代uUTI治疗的其他六种相关OC药物。