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Anaerobic blood culture positivity at a University Hospital in Hungary: A 5-year comparative retrospective study.
Anaerobe ( IF 2.5 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.anaerobe.2020.102200
Márió Gajdács 1 , Marianna Ábrók 2 , Andrea Lázár 2 , Gabriella Terhes 2 , Edit Urbán 3
Affiliation  

Anaerobic bacteremia (AB) is usually detected in about 0.5–13% of positive blood cultures. The aim of this study was to determine prevalence of anaerobic bacteremia over a 5-year period (2013–2017), to identify current trends at our University Hospital and to compare the results to those in a similar study (2005–2009) in the same region. During the study period, an average of 23,274 ± 2,756 blood cultures were received per year. Out of the positive blood cultures, 3.3–3.6% (n = 423) yielded anaerobic bacteria, representing 3.5–3.8 anaerobic isolates/1000 blood culture bottles (including both aerobic and anaerobic bottles) per year for hospitalized patients. Mean age of affected patients was 70–73 years (range: 18–102 years) with a male-to-female ratio: 0.60. Most isolated anaerobes were Cutibacterium spp. (54.0 ± 8.5%; n = 247), while among anaerobes other than Cutibacterium spp., Bacteroides and Parabacteroides and Clostridium spp. were the most prevalent. Blood culture time-to-positivity (TTP) for clinically relevant bacteria was 31.4 ± 23.4 h, while for Cutibacterium spp., TTP values were 112.9 ± 37.2 h (p < 0.0001). In conclusion, the prevalence of anaerobic bacteremia should be determined on institutional basis.



中文翻译:

匈牙利大学医院的无氧血液培养阳性:一项为期5年的比较回顾性研究。

通常在约0.5–13%的阳性血液培养物中检测到厌氧菌血症(AB)。这项研究的目的是确定5年期间(2013-2017年)的厌氧菌血症患病率,确定大学医院当前的趋势,并将结果与​​同类研究(2005-2009年)中的结果进行比较。同一地区。在研究期间,每年平均接受23274±2756次血液培养。在阳性血液培养物中,有3.3-3.6%(n = 423)产生厌氧菌,代表住院患者每年需要3.5-3.8个厌氧菌分离株/ 1000个血培养瓶(包括有氧和无氧瓶)。受影响患者的平均年龄为70-73岁(范围:18-102岁),男女之比为0.60。大多数分离的厌氧菌是角质杆菌spp。(54.0±8.5%; n = 247),而除角皮属菌,拟杆菌属细菌属和梭状芽胞杆菌属以外的厌氧菌中。是最流行的。临床相关细菌的血培养阳性时间(TTP)为31.4±23.4 h,而角皮属菌的TTP值为112.9±37.2 h(p <0.0001)。总之,应根据机构确定厌氧菌血症的患病率。

更新日期:2020-04-01
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