Organic solvent nanofiltration (OSN) is a green and cost-effective technique for valuable small active molecule reclamation from organic solvent systems. To date, it remains challenging to develop highly permeable and precisely sieving nanoporous membranes capable of working with dual solvent systems. Herein, we design polar-group-enriched conjugated nanoporous membranes (CNMs) to achieve ultrahigh performance for dual solvents. The CNMs contain sodium polymethacrylate-grafted-UiO-66 metal-organic framework (MOF) nanoparticles, which can create additional interfacial nano-pores for solvent permeation, enhance solvent affinity, and partially reduce the swelling of the CNMs. Consequently, our membranes exhibit ultrahigh permeances in dual solvents (EtOH 53.9 L m^–2 h^–1 bar^–1, H₂O 58.1 L m^–2 h^–1 bar^–1, pentane 244.0 L m^–2 h^–1 bar^–1 and hexane 172.9 L m^–2 h^–1 bar^–1) with molecular weight cut-off below 400 Da, which is superior to many state-of-the-art OSN membranes, demonstrating potential for diverse applications from pharmaceutical industry to chemical engineering.

有机溶剂纳滤（OSN）是一种绿色且经济高效的技术，可用于从有机溶剂系统回收有价值的小型活性分子。迄今为止，开发能够与双溶剂系统一起使用的高渗透性和精确筛分的纳米多孔膜仍然具有挑战性。在本文中，我们设计了富含极性基团的共轭纳米多孔膜（CNM），以实现双重溶剂的超高性能。CNM包含聚甲基丙烯酸钠接枝的UiO-66金属-有机骨架（MOF）纳米颗粒，可形成额外的界面纳米孔以渗透溶剂，增强溶剂亲和力，并部分减少CNM的溶胀。因此，我们的膜在双重溶剂（EtOH 53.9 L m ^–2 h ^–1 bar ^–1，H ₂ O 58.1 L m ^–2 h ^–1 bar ^–1，戊烷244.0 L m ^–2 h ^–1 bar ^–1和己烷172.9 L m ^–2 h ^–1 bar ^–1），分子量截止值低于400 Da优于许多最新的OSN膜，显示了从制药工业到化学工程的各种应用的潜力。