This study was designed to observe whether disparities exist between ethnicities in reporting a family history of cancer in a cancer genetic counseling clinic. Four hundred sixty‐nine pedigrees collected between 2015 to 2017 from a cancer clinic at the University of California, Irvine, were analyzed. Pedigrees were separated by ethnicity into the following categories: non‐Hispanic White, Hispanic, Asian, or Ashkenazi Jewish. The number of first‐ and second‐degree relatives was calculated for each pedigree, and the total number of relatives reported with cancer. The total reported with cancer was divided by total number of relatives to derive a percentage of cancer reporting for each pedigree. The percentages of cancer reporting were analyzed using column proportions, nonparametric tests, and a Poisson regression. Cancer reporting in first‐ and second‐degree relatives was highest among non‐Hispanic Whites and Ashkenazi Jewish individuals, with median percentages of 22% and 27%, respectively. The median percentage of cancer reporting in first‐ and second‐degree relatives in both Hispanics and Asians was 10%. Cancer reporting medians were significantly lower in Hispanics and Asians when compared to non‐Hispanic Whites and Ashkenazi Jewish individuals (p  < .001). Ethnicity was a significant factor for predicting the number of relatives reported to have cancer when analyzed with a Poisson regression. This study concluded that cancer is reported less frequently in families when the proband and their families are Hispanic or Asian. Hispanics and Asians have lower cancer incidence rates; however, incidence rates alone may not explain the reporting disparity observed. Hence, family cancer histories in minority populations may be truncated. Healthcare professionals should be aware of this disparity when assessing cancer risks so appropriate modifications can be made accordingly for recommended cancer screening and/or cancer genetic testing. Further efforts are warranted to disseminate information to minority populations about the value of family health history regarding cancer risk assessment.

中文翻译：

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家族史中报告的癌症发生率的种族差异。

这项研究旨在观察在癌症遗传咨询诊所报告癌症家族史时种族之间是否存在差异。分析了2015年至2017年间从加利福尼亚大学欧文分校的一家癌症诊所收集的469个家谱。家谱按种族分为以下几类：非西班牙裔白人，西班牙裔，亚洲裔或阿什肯纳齐犹太裔。计算每个谱系的一级和二级亲属数量，以及报告患有癌症的亲属总数。报告的癌症总数除以亲戚总数，得出每个谱系报告癌症的百分比。使用列比例，非参数检验和泊松回归分析癌症报告的百分比。非西班牙裔白人和Ashkenazi犹太人中，一级和二级亲属的癌症报告率最高，中位数分别为22％和27％。在西班牙裔和亚洲人中，一级和二级亲属报告癌症的中位百分比为10％。与非西班牙裔白人和Ashkenazi犹太人相比，西班牙裔和亚洲人的癌症报告中位数显着降低（p  <.001）。通过泊松回归分析，种族是预测报告患有癌症的亲戚人数的重要因素。这项研究得出的结论是，当先证者及其家人为西班牙裔或亚裔时，家庭中癌症的报告频率降低。西班牙裔和亚洲人的癌症发病率较低；但是，仅发病率可能无法解释观察到的报告差异。因此，少数民族人口中的家庭癌症史可能会被截断。医疗保健专业人员在评估癌症风险时应意识到这种差异，因此可以相应地进行适当的修改，以建议进行癌症筛查和/或癌症基因检测。有必要进一步努力，向少数族裔人群传播有关癌症风险评估的家庭健康史价值的信息。