Vimentin citrullination, the calcium (Ca2+)‐dependent peptidylarginine deiminase (PAD)‐mediated conversion of an arginine residue of vimentin to a citrulline residue, has emerged as a pathophysiological outcome of autoimmune diseases and neurodegeneration. However, the roles, functions, and expression of citrullinated vimentin have not yet been elucidated because available antibodies are limited.

中文翻译：

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新型单克隆抗体探测波形蛋白瓜氨酸化可作为神经变性反应性星形胶质细胞的特异性指标

波形蛋白瓜氨酸化是钙 (Ca2+) 依赖性肽基精氨酸脱亚胺酶 (PAD) 介导的波形蛋白精氨酸残基向瓜氨酸残基的转化，已成为自身免疫性疾病和神经退行性疾病的病理生理结果。然而，瓜氨酸波形蛋白的作用、功能和表达尚未阐明，因为可用的抗体有限。