Exploring white matter (WM) microstructural alterations is a momentous step for gaining insights about underlying mechanisms of obsessive‐compulsive disorder (OCD) and improving the efficacy of therapies for this condition. Many tract‐based spatial statistics (TBSS) studies have revealed abnormalities of fractional anisotropy (FA; an index of WM integrity) in OCD. However, research works have not drawn robust conclusions. Therefore, we integrated the findings of TBSS studies to identify the most consistent FA changes in OCD using meta‐analytical approach.

中文翻译：

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对基于强迫症的空间统计资料进行荟萃分析揭示了强迫症中的白质破坏。

探索白质（WM）的微结构改变是获得有关强迫症（OCD）潜在机制的见解并提高针对这种情况的治疗功效的重要一步。许多基于管道的空间统计（TBSS）研究表明，OCD中的分数各向异性（FA； WM完整性指数）异常。但是，研究工作尚未得出可靠的结论。因此，我们使用荟萃分析方法整合了TBSS研究的结果，以确定OCD中最一致的FA变化。