We aimed to evaluate the effect of dried Ziziphus vulgaris [Z. vulgaris] consumption on liver enzymes, blood pressure, inflammatory status, glycemic control, and lipid concentrations in type 2 diabetes patients. Seventy‐six diabetic participants (aged 20–65 years) randomly assigned to intervention (n = 38) and placebo (n = 38) groups. The intervention group received 30 g/day dried Z. vulgaris for 12 weeks. At the end of the study, there was a significant reduction in the percentage change of weight, body mass index [BMI], insulin, homeostasis model assessment‐insulin resistance [HOMA‐IR], Apoprotein B100 [ApoB100], and high‐sensitive c‐reactive protein [hs‐CRP] in the intervention group compared to the controls. Also, increased values of quantitative insulin check index [QUICKI] and Apoprotein A‐I [ApoA‐I] in Z. vulgaris group compared to the controls were observed. In conclusion, consumption of dried Z. vulgaris fruit could have beneficial effects on improving the glycemic control and reducing the cardiovascular risk factors in the diabetic patients.

中文翻译：

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干紫菜对 2 型糖尿病患者血糖控制、血脂、载脂蛋白和 hs-CRP 的影响：一项随机对照临床试验

我们的目的是评估干燥的Ziziphus vulgaris [ Z. vulgaris ] 食用对 2 型糖尿病患者的肝酶、血压、炎症状态、血糖控制和血脂浓度的影响。76 名糖尿病参与者（年龄 20-65 岁）被随机分配到干预组（n  = 38）和安慰剂组（n  = 38）。干预组每天服用 30 g 干燥的Z. vulgaris12周。在研究结束时，体重百分比变化、体重指数 [BMI]、胰岛素、稳态模型评估-胰岛素抵抗 [HOMA-IR]、载脂蛋白 B100 [ApoB100] 和高敏与对照组相比，干预组的 c 反应蛋白 [hs-CRP]。此外，与对照组相比，观察到普通 Z. vulgaris组的定量胰岛素检查指数 [QUICKI] 和载脂蛋白 A-I [ApoA-I] 值增加。综上所述，食用干果对改善糖尿病患者的血糖控制和降低心血管危险因素具有有益作用。