Objective:

The present study aimed to investigate the relationship between serum oxytocin (OT) and logical memory among older people in rural Japan.

Methods:

This was a cross-sectional study using a survey conducted from October 2009 through March 2011. Most of the study was conducted as part of a national prevalence survey of dementia in Japan. The final sample comprised 385 community-dwelling people aged 65 years or older living in rural Japan. The mean age and standard deviation were 75.7 ± 6.76 years (144 men, mean age 75.0 ± 6.48 years; 241 women, mean age 76.2 ± 6.91 years). The participants underwent screening examinations for a prevalence survey of dementia. The screening examinations were the Mini-Mental State Examination, Clinical Dementia Rating, and “logical memory A” from the Wechsler Memory Scale–Revised (WMSR). We used the WMSR Logical Memory II delayed recall score (LM II-DR) to assess logical memory. Levels of serum OT were obtained using the enzyme immunoassay method.

Results:

Serum OT levels were significantly higher among women than men. The present study revealed that serum OT levels were positively associated with LM II-DR in older women living in rural Japan in multiple linear regression analyses.

Conclusions:

The present results suggested a positive correlation between OT and logical memory in older women living in rural Japan.

中文翻译：

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日本农村老年人的血清催产素水平和逻辑记忆

客观的：

本研究旨在调查日本农村老年人血清催产素 (OT) 与逻辑记忆之间的关系。

方法：

这是一项横断面研究，使用了从 2009 年 10 月到 2011 年 3 月进行的一项调查。该研究的大部分是作为日本全国痴呆症患病率调查的一部分进行的。最终样本包括 385 名居住在日本农村的 65 岁或以上的社区居民。平均年龄和标准差为 75.7 ± 6.76 岁（144 名男性，平均年龄 75.0 ± 6.48 岁；241 名女性，平均年龄 76.2 ± 6.91 岁）。参与者接受了痴呆症患病率调查的筛查检查。筛查检查是​​简易精神状态检查、临床痴呆评定和韦氏记忆量表修订版 (WMSR) 中的“逻辑记忆 A”。我们使用 WMSR 逻辑记忆 II 延迟回忆分数 (LM II-DR) 来评估逻辑记忆。使用酶免疫测定法获得血清OT水平。

结果：

女性的血清 OT 水平显着高于男性。本研究表明，在多元线性回归分析中，生活在日本农村的老年妇女的血清 OT 水平与 LM II-DR 呈正相关。

结论：

目前的结果表明，生活在日本农村的老年妇女的 OT 与逻辑记忆之间存在正相关。